P28S (p.Pro28Ser) variant of FOXO1 (Forkhead box protein O1)
P28S (p.Pro28Ser) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data.
P28S (p.Pro28Ser) variant details
- p.Pro28Ser
- gnomAD rs1232364332
- Missense
- Variant Prioritization Score for Impact Estimate 0.742
- REVEL 0.70
- MetaLR 0.91
- MetaSVM 1.00
- CADD 26.30
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.4e-05)