P28R (p.Pro28Arg) variant of FOXO1 (Forkhead box protein O1)
P28R (p.Pro28Arg) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data.
P28R (p.Pro28Arg) variant details
- p.Pro28Arg
- 1000Genomes rs1182709050
- TOPMed rs1182709050
- gnomAD rs1182709050
- Missense
- Variant Prioritization Score for Impact Estimate 0.722
- REVEL 0.67
- MetaLR 0.89
- MetaSVM 0.84
- CADD 27.00
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the 1KG:MSL population (allele frequency 0.0063)