P20L (p.Pro20Leu) variant of FOXO1 (Forkhead box protein O1)
P20L (p.Pro20Leu) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data.
P20L (p.Pro20Leu) variant details
- p.Pro20Leu
- TOPMed rs1465987375
- Missense
- Variant Prioritization Score for Impact Estimate 0.591
- REVEL 0.57
- MetaLR 0.80
- MetaSVM 0.54
- CADD 23.80
- PolyPhen-2 0.06
- SIFT 0.00
- Population evidence available