P18S (p.Pro18Ser) variant of FOXO1 (Forkhead box protein O1)
P18S (p.Pro18Ser) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data.
P18S (p.Pro18Ser) variant details
- p.Pro18Ser
- TOPMed rs1006100999
- gnomAD rs1006100999
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.16
- MetaLR 0.41
- MetaSVM -0.66
- CADD 16.60
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 0.0002)