P18R (p.Pro18Arg) variant of FOXO1 (Forkhead box protein O1)
P18R (p.Pro18Arg) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data.
P18R (p.Pro18Arg) variant details
- p.Pro18Arg
- TOPMed rs1434507228
- Missense
- Variant Prioritization Score for Impact Estimate 0.454
- REVEL 0.32
- MetaLR 0.68
- MetaSVM 0.37
- CADD 22.70
- PolyPhen-2 0.22
- SIFT 0.10
- Most common in the Latino/Admixed American population (allele frequency 3.7e-05)