P12Q (p.Pro12Gln) variant of FOXO1 (Forkhead box protein O1)
P12Q (p.Pro12Gln) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data.
P12Q (p.Pro12Gln) variant details
- p.Pro12Gln
- ExAC rs773597669
- TOPMed rs773597669
- gnomAD rs773597669
- Missense
- Variant Prioritization Score for Impact Estimate 0.757
- REVEL 0.84
- MetaLR 0.90
- MetaSVM 1.02
- CADD 27.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.0042)