L77V (p.Leu77Val) variant of FOXO1 (Forkhead box protein O1)
L77V (p.Leu77Val) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data.
L77V (p.Leu77Val) variant details
- p.Leu77Val
- TOPMed rs1197474851
- gnomAD rs1197474851
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.25
- MetaLR 0.71
- MetaSVM -0.37
- CADD 20.30
- PolyPhen-2 0.01
- SIFT 0.10
- Population evidence available