L76V (p.Leu76Val) variant of FOXO1 (Forkhead box protein O1)
L76V (p.Leu76Val) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data.
L76V (p.Leu76Val) variant details
- p.Leu76Val
- 1000Genomes rs543709312
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.31
- MetaLR 0.83
- MetaSVM 0.28
- CADD 23.70
- SIFT 0.17
- Most common in the 1KG:GWD population (allele frequency 0.0043)