G88D (p.Gly88Asp) variant of FOXO1 (Forkhead box protein O1)
G88D (p.Gly88Asp) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data.
G88D (p.Gly88Asp) variant details
- p.Gly88Asp
- TOPMed rs900638210
- gnomAD rs900638210
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.14
- MetaLR 0.57
- MetaSVM -0.48
- CADD 15.10
- PolyPhen-2 0.01
- SIFT 0.63
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)