G88A (p.Gly88Ala) variant of FOXO1 (Forkhead box protein O1)
G88A (p.Gly88Ala) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data.
G88A (p.Gly88Ala) variant details
- p.Gly88Ala
- TOPMed rs900638210
- gnomAD rs900638210
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.18
- MetaLR 0.51
- MetaSVM -0.53
- CADD 13.30
- PolyPhen-2 0.00
- SIFT 0.77
- Most common in the Amish population (allele frequency 0.0022)