G112S (p.Gly112Ser) variant of FOXO1 (Forkhead box protein O1)
G112S (p.Gly112Ser) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data.
G112S (p.Gly112Ser) variant details
- p.Gly112Ser
- Ensembl rs1878223078
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.11
- MetaLR 0.55
- MetaSVM -0.52
- CADD 15.60
- PolyPhen-2 0.01
- SIFT 0.52
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)