G105E (p.Gly105Glu) variant of FOXO1 (Forkhead box protein O1)
G105E (p.Gly105Glu) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G105E (p.Gly105Glu) variant details
- p.Gly105Glu
- TOPMed rs1333425848
- gnomAD rs1333425848
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.22
- MetaLR 0.63
- MetaSVM -0.35
- CADD 12.50
- PolyPhen-2 0.01
- SIFT 0.50
- Most common in the REMAINING population (allele frequency 2.6e-05)
- Structural context available