F32V (p.Phe32Val) variant of FOXO1 (Forkhead box protein O1)
F32V (p.Phe32Val) in FOXO1 (Forkhead box protein O1) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1.
F32V (p.Phe32Val) variant details
- p.Phe32Val
- rs1391345095
- ClinGen CA388007556
- ClinVar RCV004394398
- TOPMed rs1391345095
- Uncertain significance
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- AlphaMissense 0.15
- MetaLR 0.62
- MetaSVM -0.09
- PolyPhen-2 0.27
- SIFT 0.09
- MutPred 0.24
- ClinVar: Uncertain significance (not specified)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance