E81K (p.Glu81Lys) variant of FOXO1 (Forkhead box protein O1)
E81K (p.Glu81Lys) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data.
E81K (p.Glu81Lys) variant details
- p.Glu81Lys
- gnomAD rs1878231900
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.29
- MetaLR 0.69
- MetaSVM -0.08
- CADD 22.20
- PolyPhen-2 0.15
- SIFT 0.04
- Most common in the South Asian population (allele frequency 0.00021)