E15Q (p.Glu15Gln) variant of FOXO1 (Forkhead box protein O1)
E15Q (p.Glu15Gln) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data.
E15Q (p.Glu15Gln) variant details
- p.Glu15Gln
- gnomAD rs1403000835
- Missense
- Variant Prioritization Score for Impact Estimate 0.581
- REVEL 0.47
- MetaLR 0.88
- MetaSVM 0.92
- CADD 23.70
- PolyPhen-2 0.65
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 3.8e-05)