D53N (p.Asp53Asn) variant of FOXO1 (Forkhead box protein O1)
D53N (p.Asp53Asn) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data.
D53N (p.Asp53Asn) variant details
- p.Asp53Asn
- TOPMed rs1350774254
- gnomAD rs1350774254
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.17
- MetaLR 0.67
- MetaSVM -0.01
- CADD 22.40
- PolyPhen-2 0.04
- SIFT 0.37
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)