D53H (p.Asp53His) variant of FOXO1 (Forkhead box protein O1)
D53H (p.Asp53His) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data.
D53H (p.Asp53His) variant details
- p.Asp53His
- TOPMed rs1350774254
- gnomAD rs1350774254
- Missense
- Variant Prioritization Score for Impact Estimate 0.443
- REVEL 0.27
- MetaLR 0.74
- MetaSVM 0.36
- CADD 24.80
- PolyPhen-2 0.49
- SIFT 0.09
- Most common in the REMAINING population (allele frequency 2.1e-05)