C107Y (p.Cys107Tyr) variant of FOXO1 (Forkhead box protein O1)
C107Y (p.Cys107Tyr) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data.
C107Y (p.Cys107Tyr) variant details
- p.Cys107Tyr
- gnomAD rs1878223994
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.27
- MetaLR 0.68
- MetaSVM -0.16
- CADD 18.90
- PolyPhen-2 0.14
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)