A98V (p.Ala98Val) variant of FOXO1 (Forkhead box protein O1)
A98V (p.Ala98Val) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
A98V (p.Ala98Val) variant details
- p.Ala98Val
- TOPMed rs1334866177
- gnomAD rs1334866177
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.18
- MetaLR 0.52
- MetaSVM -0.56
- CADD 12.70
- PolyPhen-2 0.03
- SIFT 0.46
- Most common in the African/African-American population (allele frequency 7.3e-05)
- Structural context available