A97E (p.Ala97Glu) variant of FOXO1 (Forkhead box protein O1)
A97E (p.Ala97Glu) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data.
A97E (p.Ala97Glu) variant details
- p.Ala97Glu
- TOPMed rs970471060
- gnomAD rs970471060
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.22
- MetaLR 0.54
- MetaSVM -0.54
- CADD 5.85
- PolyPhen-2 0.03
- SIFT 0.47
- Most common in the African/African-American population (allele frequency 7.3e-05)