A91V (p.Ala91Val) variant of FOXO1 (Forkhead box protein O1)
A91V (p.Ala91Val) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data.
A91V (p.Ala91Val) variant details
- p.Ala91Val
- TOPMed rs1284681540
- gnomAD rs1284681540
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.27
- MetaLR 0.64
- MetaSVM -0.40
- CADD 15.60
- PolyPhen-2 0.01
- SIFT 0.43
- Most common in the REMAINING population (allele frequency 4.7e-05)