A61V (p.Ala61Val) variant of FOXO1 (Forkhead box protein O1)
A61V (p.Ala61Val) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data.
A61V (p.Ala61Val) variant details
- p.Ala61Val
- TOPMed rs899092289
- gnomAD rs899092289
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.17
- MetaLR 0.71
- MetaSVM -0.23
- CADD 18.00
- PolyPhen-2 0.01
- SIFT 0.32
- Most common in the REMAINING population (allele frequency 0.00048)