A50D (p.Ala50Asp) variant of FOXO1 (Forkhead box protein O1)
A50D (p.Ala50Asp) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data.
A50D (p.Ala50Asp) variant details
- p.Ala50Asp
- TOPMed rs1003365110
- gnomAD rs1003365110
- Missense
- Variant Prioritization Score for Impact Estimate 0.395
- REVEL 0.19
- MetaLR 0.57
- MetaSVM -0.46
- CADD 17.80
- PolyPhen-2 0.02
- SIFT 0.47
- Population evidence available