A4V (p.Ala4Val) variant of FOXO1 (Forkhead box protein O1)
A4V (p.Ala4Val) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data.
A4V (p.Ala4Val) variant details
- p.Ala4Val
- Ensembl rs1878246313
- Missense
- Variant Prioritization Score for Impact Estimate 0.575
- REVEL 0.44
- MetaLR 0.75
- MetaSVM 0.76
- CADD 21.70
- PolyPhen-2 0.36
- SIFT 0.27
- Most common in the REMAINING population (allele frequency 1.9e-05)