A38V (p.Ala38Val) variant of FOXO1 (Forkhead box protein O1)
A38V (p.Ala38Val) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data.
A38V (p.Ala38Val) variant details
- p.Ala38Val
- TOPMed rs956635931
- gnomAD rs956635931
- Missense
- Variant Prioritization Score for Impact Estimate 0.425
- REVEL 0.24
- MetaLR 0.63
- MetaSVM -0.30
- CADD 22.80
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the African/African-American population (allele frequency 0.00012)