A100V (p.Ala100Val) variant of FOXO1 (Forkhead box protein O1)
A100V (p.Ala100Val) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A100V (p.Ala100Val) variant details
- p.Ala100Val
- gnomAD rs1878226648
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.31
- MetaLR 0.47
- MetaSVM -0.35
- CADD 7.11
- PolyPhen-2 0.02
- SIFT 0.53
- Most common in the Non-Finnish European population (allele frequency 8.9e-06)
- Structural context available