Y55H (p.Tyr55His) variant of FOXI1 (Forkhead box protein I1)
Y55H (p.Tyr55His) in FOXI1 (Forkhead box protein I1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
Y55H (p.Tyr55His) variant details
- p.Tyr55His
- gnomAD 5-170106120-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.644
- REVEL 0.71
- MetaLR 0.87
- MetaSVM 0.91
- CADD 25.40
- PolyPhen-2 0.89
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available