S15N (p.Ser15Asn) variant of FOXI1 (Forkhead box protein I1)
S15N (p.Ser15Asn) in FOXI1 (Forkhead box protein I1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
S15N (p.Ser15Asn) variant details
- p.Ser15Asn
- NCI-TCGA Cosmic COSV6038
- cosmic curated COSV60388
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- REVEL 0.41
- CADD 23.20
- PolyPhen-2 0.52
- SIFT 0.25
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available