Q45H (p.Gln45His) variant of FOXI1 (Forkhead box protein I1)
Q45H (p.Gln45His) in FOXI1 (Forkhead box protein I1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
Q45H (p.Gln45His) variant details
- p.Gln45His
- NCI-TCGA TCGA novel
- TOPMed rs941579883
- gnomAD rs941579883
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.46
- CADD 23.60
- PolyPhen-2 0.94
- SIFT 0.03
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available