P25L (p.Pro25Leu) variant of FOXI1 (Forkhead box protein I1)
P25L (p.Pro25Leu) in FOXI1 (Forkhead box protein I1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
P25L (p.Pro25Leu) variant details
- p.Pro25Leu
- cosmic curated COSV10883
- Ensembl rs1758467063
- Missense
- Variant Prioritization Score for Impact Estimate 0.503
- REVEL 0.35
- CADD 20.30
- PolyPhen-2 0.04
- SIFT 0.21
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available