P25H (p.Pro25His) variant of FOXI1 (Forkhead box protein I1)
P25H (p.Pro25His) in FOXI1 (Forkhead box protein I1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
P25H (p.Pro25His) variant details
- p.Pro25His
- gnomAD 5-170106031-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.664
- REVEL 0.52
- MetaLR 0.87
- MetaSVM 0.91
- CADD 24.30
- PolyPhen-2 0.94
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available