P19L (p.Pro19Leu) variant of FOXI1 (Forkhead box protein I1)
P19L (p.Pro19Leu) in FOXI1 (Forkhead box protein I1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data, published literature, and structural context.
P19L (p.Pro19Leu) variant details
- p.Pro19Leu
- gnomAD 5-170106013-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.732
- REVEL 0.65
- MetaLR 0.88
- MetaSVM 0.93
- CADD 25.20
- PolyPhen-2 0.88
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available