L6V (p.Leu6Val) variant of FOXI1 (Forkhead box protein I1)
L6V (p.Leu6Val) in FOXI1 (Forkhead box protein I1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
L6V (p.Leu6Val) variant details
- p.Leu6Val
- gnomAD 5-170105973-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- REVEL 0.27
- CADD 16.70
- PolyPhen-2 0.07
- SIFT 0.42
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- Literature evidence available