L6R (p.Leu6Arg) variant of FOXI1 (Forkhead box protein I1)
L6R (p.Leu6Arg) in FOXI1 (Forkhead box protein I1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
L6R (p.Leu6Arg) variant details
- p.Leu6Arg
- gnomAD 5-170105974-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.36
- REVEL 0.30
- CADD 22.40
- PolyPhen-2 0.22
- SIFT 0.19
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available