I21T (p.Ile21Thr) variant of FOXI1 (Forkhead box protein I1)
I21T (p.Ile21Thr) in FOXI1 (Forkhead box protein I1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
I21T (p.Ile21Thr) variant details
- p.Ile21Thr
- gnomAD 5-170106019-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.42
- REVEL 0.28
- MetaLR 0.62
- MetaSVM 0.06
- CADD 20.50
- PolyPhen-2 0.06
- SIFT 0.61
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available
- Literature evidence available