F4L (p.Phe4Leu) variant of FOXI1 (Forkhead box protein I1)
F4L (p.Phe4Leu) in FOXI1 (Forkhead box protein I1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
F4L (p.Phe4Leu) variant details
- p.Phe4Leu
- NCI-TCGA Cosmic COSV6038
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.467
- REVEL 0.51
- CADD 22.60
- PolyPhen-2 0.20
- SIFT 0.02
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available