E33K (p.Glu33Lys) variant of FOXI1 (Forkhead box protein I1)
E33K (p.Glu33Lys) in FOXI1 (Forkhead box protein I1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
E33K (p.Glu33Lys) variant details
- p.Glu33Lys
- gnomAD 5-170106054-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.695
- REVEL 0.62
- MetaLR 0.80
- MetaSVM 0.76
- CADD 24.60
- PolyPhen-2 0.27
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available