P25S (p.Pro25Ser) variant of FOXG1 (Forkhead box protein G1)
P25S (p.Pro25Ser) in FOXG1 (Forkhead box protein G1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
P25S (p.Pro25Ser) variant details
- p.Pro25Ser
- gnomAD 14-28767352-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.14
- MetaLR 0.17
- MetaSVM -0.83
- CADD 24.10
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.7e-07)
- Structural context available
- Literature evidence available