P25L (p.Pro25Leu) variant of FOXG1 (Forkhead box protein G1)
P25L (p.Pro25Leu) in FOXG1 (Forkhead box protein G1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
P25L (p.Pro25Leu) variant details
- p.Pro25Leu
- gnomAD 14-28767353-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.20
- MetaLR 0.16
- MetaSVM -0.85
- CADD 24.40
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.7e-07)
- Structural context available
- Literature evidence available