Y26C (p.Tyr26Cys) variant of FOXA1 (P55317)
Y26C (p.Tyr26Cys) in FOXA1 (P55317) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data.
Y26C (p.Tyr26Cys) variant details
- p.Tyr26Cys
- ExAC rs771360009
- TOPMed rs771360009
- gnomAD rs771360009
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.39
- MetaLR 0.18
- MetaSVM -1.05
- CADD 29.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00033)