T60I (p.Thr60Ile) variant of FOXA1 (P55317)
T60I (p.Thr60Ile) in FOXA1 (P55317) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data.
T60I (p.Thr60Ile) variant details
- p.Thr60Ile
- TOPMed rs2095597141
- Missense
- Variant Prioritization Score for Impact Estimate 0.674
- REVEL 0.55
- MetaLR 0.81
- MetaSVM 0.66
- CADD 27.50
- PolyPhen-2 0.74
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)