Y63Y (p.Tyr63Tyr) variant of FLNB (Filamin-B)
Y63Y (p.Tyr63Tyr) in FLNB (Filamin-B) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Y63Y (p.Tyr63Tyr) variant details
- p.Tyr63Tyr
- gnomAD 3-58008753-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.465
- CADD 14.10
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- FLNB Filamin/ABP280 repeat-like domain domainome 1.0: score -0.0574
- Literature evidence available