T21T (p.Thr21Thr) variant of FLNB (Filamin-B)
T21T (p.Thr21Thr) in FLNB (Filamin-B) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T21T (p.Thr21Thr) variant details
- p.Thr21Thr
- rs539469179
- gnomAD 3-58008627-G-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.137
- CADD 7.97
- Most common in the Latino/Admixed American population (allele frequency 9e-05)
- Structural context available
- FLNB Filamin/ABP280 repeat-like domain domainome 1.0: score 0.0429
- Literature evidence available