R64R (p.Arg64Arg) variant of FLNB (Filamin-B)
R64R (p.Arg64Arg) in FLNB (Filamin-B) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R64R (p.Arg64Arg) variant details
- p.Arg64Arg
- gnomAD 3-58008756-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.59
- CADD 16.10
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- FLNB Filamin/ABP280 repeat-like domain domainome 1.0: score -0.0825
- Literature evidence available