K65K (p.Lys65Lys) variant of FLNB (Filamin-B)
K65K (p.Lys65Lys) in FLNB (Filamin-B) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
K65K (p.Lys65Lys) variant details
- p.Lys65Lys
- rs2106655440
- gnomAD 3-58008759-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.354
- CADD 15.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- FLNB Filamin/ABP280 repeat-like domain domainome 1.0: score -0.431
- Literature evidence available