K31M (p.Lys31Met) variant of FLNB (Filamin-B)
K31M (p.Lys31Met) in FLNB (Filamin-B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data, experimental measurements, and structural context.
K31M (p.Lys31Met) variant details
- p.Lys31Met
- ExAC rs759061129
- gnomAD rs759061129
- Missense
- Variant Prioritization Score for Impact Estimate 0.761
- REVEL 0.82
- CADD 32.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- FLNB Filamin/ABP280 repeat-like domain domainome 1.0: score -0.316