E10E (p.Glu10Glu) variant of FLNB (Filamin-B)
E10E (p.Glu10Glu) in FLNB (Filamin-B) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
E10E (p.Glu10Glu) variant details
- p.Glu10Glu
- gnomAD 3-58008594-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.663
- CADD 14.40
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- FLNB Filamin/ABP280 repeat-like domain domainome 1.0: score -0.23
- Literature evidence available