Y94N (p.Tyr94Asn) variant of FGG (Fibrinogen gamma chain)
Y94N (p.Tyr94Asn) in FGG (Fibrinogen gamma chain) is a missense change. Clinical records from ClinVar and UniProt describe it as conflicting interpretations in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
Y94N (p.Tyr94Asn) variant details
- p.Tyr94Asn
- ExAC rs770096313
- TOPMed rs770096313
- gnomAD rs770096313
- Conflicting interpretations
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.47
- CADD 17.60
- PolyPhen-2 0.29
- SIFT 0.15
- ClinVar: Conflicting classifications of pathogenicity (not provided)
- UniProt: Conflicting interpretations
- Most common in the HGDP:PIMA population (allele frequency 0.045)
- Structural context available