Y27C (p.Tyr27Cys) variant of FGG (Fibrinogen gamma chain)
Y27C (p.Tyr27Cys) in FGG (Fibrinogen gamma chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
Y27C (p.Tyr27Cys) variant details
- p.Tyr27Cys
- gnomAD rs1163362139
- Missense
- Variant Prioritization Score for Impact Estimate 0.547
- REVEL 0.37
- CADD 23.80
- PolyPhen-2 0.72
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available