Y122C (p.Tyr122Cys) variant of FGG (Fibrinogen gamma chain)
Y122C (p.Tyr122Cys) in FGG (Fibrinogen gamma chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
Y122C (p.Tyr122Cys) variant details
- p.Tyr122Cys
- TOPMed rs1333386404
- gnomAD rs1333386404
- Missense
- Variant Prioritization Score for Impact Estimate 0.517
- REVEL 0.53
- CADD 27.10
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available